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Ginsenoside Rh3

Ginsenoside Rh3

CAS : 105558-26-7
Molecular Formula : C37H62O7 
Formula Weight : 604.86g/mol
Description : 
Ginsenosides Rg5 and Rh3 suppressed swelling of oxazolone-induced mouse ear contact dermatitis. These ginsenosides also reduced mRNA expressions of cyclooxygenase-2, interleukin (IL)-1β, tumor necrosis factor (TNF)-α and interferon (IFN)-γ. The inhibition of ginsenoside Rh3 was more potent than that of ginsenoside Rg5. These findings suggest that ginsenoside Rh3 metabolized from ginsenoside Rg5 may improve chronic dermatitis or psoriasis by the regulation of IL-1β and TNF-α produced by macrophage cells and of IFN-γ produced by Th cells.

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