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Atractylenolide I

Atractylenolide I

CAS : 73069-13-3
Molecular Formula : C15H20O3
Formula Weight : 248.32g/mol
Description :
Atractylenolide I is an anti-inflammation agent.It could dose-dependently inhibit the production of nitric oxide (NO), tumor necrosis factor-α (TNF-α), interleukin-1β (IL-1β), interleukin-6 (IL-6), vascular endothelial growth factor (VEGF) and placenta growth factor (PlGF) activity in the flute of mouse air pouch and the peritoneal macrophages stimulated by lipopolysaccharide (LPS). Atractylenolide I displayed a potent inhibitory effect on angiogenesis by a set of down-regulatory actions of NO, TNF-α, IL-1β, IL-6, VEGF and PlGF in chronic inflammation.

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