Emetine dihydrochloride hydrate
CAS : 316-42-7
Molecular Formula : C29H44Cl2N2O5
Formula Weight : 571.58g/mol
Emetine inhibits protein synthesis in eukaryotic cells by binding to the 40S ribosomal subunit and inhibiting translocation.The use and effect on protein synthesis has been extensively reported.When emetine is added to a suspension of HeLa cells or reticuloycytes, polyribosomes increase and single ribosomes decrease. Protein synthesis is inhibited irreversibly, possibly by affecting an aspect of translocation that involves movement of mRNA along the ribosome.
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