CAS : 7689-03-4
Molecular Formula : C20H16N2O4
Formula Weight : 348.35
Camptothecin is a cytotoxic quinoline alkaloid which inhibits the DNA enzyme topoisomerase I .
Usage: Antitumor alkaloid. Binds irreversible to the DNA-topoisomerase I complex, inhibiting the reassociation of DNA after cleavage by topoisomerase I and traps the enzyme in a covalent linkage with DNA. A cytotoxic antitumor agent
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