CAS : 14976-57-9
Molecular Formula : C25H30ClNO5
Formula Weight : 459.96
Clemastine fumarate belongs to the benzhydryl ether group of antihistaminic compounds. The chemical name is (+)-2-[-2- [(p-chloro-α-methyl-α-phenylbenzyl) oxy] ethyl]-1-methylpyrrolidine hydrogen fumarate.Clemastine fumarate is an antihistamine with anticholinergic (drying) and sedative side effects. Antihistamines appear to compete with histamine for cell receptor sites on effector cells. The inherently long duration of antihistaminic effects of Clemastine has been demonstrated in wheal and flare studies. In normal human subjects who received histamine injections over a 24-hour period, the antihistaminic activity of Clemastine reached a peak at 5 to 7 hours, persisted for 10 to 12 hours and, in some cases, for as long as 24 hours.
Send enquiry online
After send online enquiry, we will reply you as soon as possible, if not get any response on time please contact us by Tel or Email.
Tel: +86 592 5365868
WhatsApp: +86 189 6516 2351