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Astemizole

Astemizole

CAS : 68844-77-9
Molecular Formula : C28H31FN4O
Formula Weight : 458.57
Description : 
Astemizole (marketed under the brand name Hismanal) was a second generation antihistamine drug which has a long duration of action. Astemizole was discovered by Janssen Pharmaceutica in 1977. It has been withdrawn from the market in most countries because of rare but potentially fatal side effects.It has been reported that this drug might prevent much of the muscle wasting (atrophy) that occurs in immobile, bedridden patients.Astemizole has recently been found to be a potent treatment for malaria. It has a mechanism of action similar to chloroquine but has activity even in chloroquine-resistant parasites.

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