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Amiloride hydrochloride

Amiloride hydrochloride

CAS : 2016-88-8
Molecular Formula : C6H11Cl2N7O2
Formula Weight : 284.1
Description :
Amiloride hydrochloride is a potassium-sparing diuretic with antihypertensive activity. Its prototype is spironolactone. 
indication :It is prescribed as an adjunct in the treatment of congestive heart failure or hypertension. It is often given with a thiazide medication. 
contraindications: Concurrent use of potassium-conserving agents, hyperkalemia, impaired renal function, or known hypersensitivity to this drug prohibit its use. 
adverse effects: Among the most serious adverse reactions are headache, diarrhea, nausea and vomiting, anorexia, hyperkalemia, dizziness, encephalopathy, impotence, muscle cramps, photosensitivity, irregular heart rhythm, confusion, and paresthesia. 
Product Categories: Active Pharmaceutical Ingredients;Ion transporter and other ion channel;Ion Channels 
mp:  293-294°C 
solubility : H2O: 50 mg/mL, clear, yellow-green 
form : powder 
color:  yellow
Water Solubility : <0.1 g/100 mL at 19.5 oC 

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